UK’s first baby born after uterus transplant « Euro Weekly News

Grace Davidson with baby Amy and the team at Queen Charlotte’s and Chelsea Hospital in London, celebrating the UK’s first birth following a womb transplant.
Credit : X – Imperial NHS 💙
@ImperialNHS
A British woman has given birth to a healthy baby girl following a uterus transplant from her sister — a first in the UK and a powerful breakthrough in fertility and reproductive medicine.
Grace Davidson, 36, who was born without a uterus due to a rare congenital condition, gave birth to little Amy Isabel on 27 February 2025 at Queen Charlotte’s and Chelsea Hospital in London. The birth comes two years after she received a donated uterus from her older sister, Amy Purdie, 42, already a mother of two.
“I couldn’t have wished for a greater gift,” said Grace, calling the moment she held her daughter “the most beautiful miracle we could have hoped for.”
Turning a rare uterus condition into a fertility breakthrough
Grace was diagnosed in her teens with MRKH syndrome, a rare disorder affecting around 1 in 5,000 women, which causes the uterus to be underdeveloped or entirely absent. While her ovaries remained functional, she was told she would never carry a child — until now.
In February 2023, a team led by surgeons Isabel Quiroga and Richard Smith at the Oxford Transplant Centre performed the complex transplant surgery. Following months of recovery and immunosuppressive therapy to prevent rejection, an embryo created via IVF was implanted.
The little girl’s name, Amy Isabel, pays tribute not only to her aunt — the organ donor — but also to the surgeon who made the procedure possible.
Shaping the future of fertility with groundbreaking womb transplants
Globally, over 100 uterus transplants have been performed since the first successful procedure in Sweden in 2013. Around 50 babies have since been born thanks to the pioneering surgery, offering fresh hope to women once told they’d never experience pregnancy.
“This is a moment of pure joy,” said Professor Richard Smith, who has worked for more than 25 years on developing the UK’s living donor transplant programme. “We finally have a baby born in Britain through this extraordinary method.”
Grace and her husband hope their story will inspire more research and access to this treatment, which could transform lives for generations to come.
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